How does an engine that is made to run on E85 differ from a normal gasoline engine?

How does an engine that is made to run on E85 differ from a normal gasoline engine?
An engine that is made to run on E85 differs from a normal gasoline engine in several ways. An engine that is made to run on E85 uses E85 as a biological fuel source whereas a normal gasoline engine that is made to run on normal gasoline runs on or uses gasoline--that is gasoline or natural gas. Both engines' designing mechanisms differ accordingly. For instance, an E85 engine's mechanisms allow it to operate on only ethanol gas but a normal gasoline engine can work on normal gasoline. Notably both engines would look different as their operative mechanisms are designed to operate differently by running on different fuel ingredients and substances. But not necessarily. This may not be likely for an engine's typicality and normality. Engines do look different in many ways but not always; they may also look the same, and in fact they do. In the case of these two engines, the question is not about whether they look different but rather if they work differently. An internal combustion engine--a typical gasoline-based engine--is an example of a normal gasoline engine. It is one of the oldest types of engines used in running motoring machines. Therefore, the many ways in which an engine that is made to run on E85 differs from a normal gasoline engine are functionality, look, design, and capacity in particular.
The way in which an engine that is made to run on E85 differs from a normal gasoline engine is in terms of its power source and the way it works or its way of working.