Does the size of the wheels on a car make a difference to its speed?

Does the size of the wheels on a car make a difference to its speed?
Yes.
Small changes are OK, but mess with the wheel size enough and it'll be like driving in another gear - which will influence the speed.
If two cars have the same engine RPM and the same transmission,
then the one with larger wheels will move down the road faster - if the engine has torque enough.